Renfang Taylor, Ph.D.

Education

  • Ph.D. in Environmental Engineering, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences
    • Dissertation: Basic Investigation of the Genotoxicity and Cellular Toxicology by Environmental Phenyl glycidyl ether (PGE) and polybrominated diphenyl ethers (PBDEs) Organic Pollutants 
  • B.Sc. in Fine Chemistry, Shandong Institute of Light Industry

Selected Publications

  • Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension.  Song Renfang, Kidd L, Janssen A, Yosypiv IV.  Physiol Rep. 2018 Apr;6(7):e13644. doi: 10.14814/phy2.13644.
  • Foxd1 is an upstream regulator of the renin-angiotensin system during metanephric kidney development.  Song Renfang, Lopez MLSS, Yosypiv IV.  Pediatr Res. 2017 Nov;82(5):855-862.
  • Prorenin receptor controls renal branching morphogenesis via Wnt/β-catenin signaling.  Song Renfang, Janssen A, Li Y, El-Dahr S, Yosypiv IV.  Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F407-F417.
  • Prorenin receptor is critical for nephron progenitors.  Song Renfang, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV.  Dev Biol. 2016 Jan 15;409(2):382-91.
  • Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia.  Song Renfang, Preston G, Ichihara A, Yosypiv IV.  PLoS One. 2013 May 21;8(5):e63835
  • Ontogeny of the (pro)renin receptor.  Song Renfang, Preston G, Yosypiv IV.  Pediatr Res. 2013 Jul;74(1):5-10.
  • Development of the kidney medulla.  Song Renfang, Yosypiv IV.  Organogenesis. 2012 Jan-Mar;8(1):10-7.
  • Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells.  Song Renfang, Duarte TL, Almeida GM, Farmer PB, Cooke MS, Zhang W, Sheng G, Fu J, Jones GD.  Toxicol Lett. 2009 Feb 25;185(1):23-31.

Selected Presentations

  • Oral Presentation: Song, Renfang; Janssen, Adam T.; Kidd, Laura R.; Yosypiv, Ihor V Conditional Ablation of the Prorenin Receptor (PRR) in Nephron Progenitor Cells (NPCs) Results in Developmental Programming of Hypertension. American Society of Nephrology (ASN kidney week 2017 New Orleans)
  • Oral Presentation: Song Rengang, Castillo A and Yosypiv IV. Reduced prorenin receptor (PRR) gene dosage in nephron progenitors in mice programs hypertension later in life. Southern Society of Pediatric  Research  Feb. 2017 New Orleans
  • Oral Presentation:Song Renfang, Graeme Preston, Ihor V. Yosypiv. Ret is a direct positively regulated target of angiotensin II (Ang II) in the ureteric bud (UB). (trainee travel reward at Southern Society of Pediatric  Research  Feb. 2015 New Orleans) 
  • Oral Presentation:Song Renfang, Riedl L and Yosypiv I. Dot1/H3K79 pathway mediates defective ureteric bud branching leading to renal hypodysplasia in prorenin receptor PRRUB-/-mice.( trainee travel reward at Southern Society of Pediatric  Research  Feb. 2014 New Orleans) 
  • Poster Presentation:Song Renfang, Preston G, Yosypiv IV. Prorenin Receptor Signaling Promotes Nephron Induction During Mouse Kidney Development. (South Society of Pediatrics. 2016 New Orleans)
  • Poster Presentataion:Song Renfang, Preston G, Yosypiv IV. Prorenin Receptor Signaling Promotes Nephron Induction During Mouse Kidney Development.( ASN Kidney Week 2015 Annual Meeting Nov. 2015; San Diego, CA)
  • Poster Presentation: Song Renfang, Preston G, Yosypiv IV. Mutations in Renin-Angiotensin System (RAS) Genes Are Associated With Isolated Multicystic Dysplastic Kidney (MCDK) in Children.( ASN Kidney Week 2013 Annual Meeting,  Nov. 2013; Atlanta, GA)
  • Poster Presentation: Song Renfang, Preston G, Yosypiv IV. Ureteric Bud (UB) Prorenin Receptor (PRR) Is Essential for Normal Collecting Duct (CD) Development and Function. (ASN Kidney Week 2013 Annual Meeting, Nov. 2013; Atlanta, GA)

Professional Organizations

  • American Society of Nephrology (ASN), 2009-present
  • American Association for the Advancement of Science (AAAS), 2008-2016
  • Southern Society of Paediatric Research (SSPR), 2009-present

Honors and Awards

  • SSCI Nephrology Young Investigators' Forum Invited Speaker, 2017
  • SSPR/APA Trainee Travel Award Winner, OGPS Travel Grant Reward, 2016
  • SSPR/APA Trainee Travel Award Winner, 2015
  • SSPR/APA Trainee Travel Award Winner, 2014
  • ASN Advances in Research Conference-Building A Kidney, Travel Grant, 2014
  • SSPR/APA Young Investigator Award, 2013
  • ASN Professional Development Seminar, Travel Grant, 2013
  • Top Oral Abstracts by Trainees for the ASN Kidney Week, 2012 Annual Meeting, Nov. 1-4 in San Diego, Calif, 2012